CALL FOR PAPERS Mathematical Modeling of Renal Function An online tool for calculation of free-energy balance for the renal inner medulla
نویسندگان
چکیده
Ryan L. Vilbig, Abhijit Sarkar, Joseph Zischkau, Mark A. Knepper, and Trairak Pisitkun Epithelial Systems Biology Laboratory, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland; Department of Physics, The Catholic University of America, Washington, District of Columbia; and Vitreous State Laboratory, The Catholic University of America, Washington, District of Columbia
منابع مشابه
An online tool for calculation of free-energy balance for the renal inner medulla.
Concentrating models of the renal inner medulla can be classified according to external free-energy balance into passive models (positive values) and models that require an external energy source (negative values). Here we introduce an online computational tool that implements the equations of Stephenson and colleagues (Stephenson JL, Tewarson RP, Mejia R. Proc Natl Acad Sci USA 71: 1618-1622, ...
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Although the concentrating process in the renal outer medulla is well understood, the concentrating mechanism in the renal inner medulla remains an enigma. The purposes of this review are fourfold. 1) We summarize a theoretical basis for classifying all possible steady-state inner medullary countercurrent concentrating mechanisms based on mass balance principles. 2) We review the major hypothes...
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Fry BC, Edwards A, Sgouralis I, Layton AT. Impact of renal medullary three-dimensional architecture on oxygen transport. Am J Physiol Renal Physiol 307: F263–F272, 2014. First published June 4, 2014; doi:10.1152/ajprenal.00149.2014.—We have developed a highly detailed mathematical model of solute transport in the renal medulla of the rat kidney to study the impact of the structured organization...
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